BDBM421650 3-((6-cyano-1-isopropyl-5- (trifluoromethyl)-1H-benzo[d]imidazol-2- yl)amino)-N-hydroxybenzamide::US10508088, Example 14-1::US10538496, Compound 18-1

SMILES CC(C)n1c(Nc2cccc(c2)C(=O)NO)nc2cc(c(cc12)C#N)C(F)(F)F

InChI Key InChIKey=XHUMGJUZIOCGJT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 421650   

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421650(3-((6-cyano-1-isopropyl-5- (trifluoromethyl)-1H-be...)
Affinity DataIC50: <500nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421650(3-((6-cyano-1-isopropyl-5- (trifluoromethyl)-1H-be...)
Affinity DataIC50: <500nMAssay Description:The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421650(3-((6-cyano-1-isopropyl-5- (trifluoromethyl)-1H-be...)
Affinity DataIC50: <500nMAssay Description:The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent