BDBM421713 4-(2-((3- (hydroxycarbamoyl)phenyl)amino)-5- (trifluoromethyl)-1H-benzo[d]imidazol-6- yl)-N,N-dimethylbenzamide::US10508088, Example 36-6::US10538496, Compound 36-6

SMILES CN(C)C(=O)c1ccc(cc1)-c1cc2[nH]c(Nc3cccc(c3)C(=O)NO)nc2cc1C(F)(F)F

InChI Key InChIKey=ZIZGMLOCZNSTQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421713   

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421713(US10538496, Compound 36-6 | US10508088, Example 36...)
Affinity DataIC50: 500nMAssay Description:The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421713(US10538496, Compound 36-6 | US10508088, Example 36...)
Affinity DataIC50: 500nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
US Patent