BDBM421716 3-((6-(2,3-dihydrobenzo[b][1,4]dioxin-6- yl)-5-(trifluoromethyl)-1H- benzo[d]imidazol-2-yl)amino)-N- hydroxybenzamide::US10508088, Example 36-9

SMILES ONC(=O)c1cccc(Nc2nc3cc(c(cc3[nH]2)-c2ccc3OCCOc3c2)C(F)(F)F)c1

InChI Key InChIKey=QKLHLOKJJQJVFL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 421716   

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421716(US10508088, Example 36-9 | 3-((6-(2,3-dihydrobenzo...)
Affinity DataIC50: 500nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
US Patent