BDBM421720 N-hydroxy-3-((6-(2-morpholinopyrimidin- 5-yl)-5-(trifluoromethyl)-1H- benzo[d]imidazol-2-yl)amino)benzamide::US10508088, Example 36-13::US10538496, Compound 36-13

SMILES ONC(=O)c1cccc(Nc2nc3cc(c(cc3[nH]2)-c2cnc(nc2)N2CCOCC2)C(F)(F)F)c1

InChI Key InChIKey=HDRZVDOJEMPOSY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421720   

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421720(US10538496, Compound 36-13 | US10508088, Example 3...)
Affinity DataIC50: 500nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421720(US10538496, Compound 36-13 | US10508088, Example 3...)
Affinity DataIC50: 500nMAssay Description:The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent