BDBM421836 US10493060, Example BVD-523

SMILES CC(C)Nc1cc(-c2c[nH]c(c2)C(=O)NC(CO)c2cccc(Cl)c2)c(Cl)cn1

InChI Key InChIKey=KSERXGMCDHOLSS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421836   

TargetMitogen-activated protein kinase 3(Human)
Recurium Ip Holdings

US Patent
LigandPNGBDBM421836(US10493060, Example BVD-523)
Affinity DataIC50: 50nMAssay Description:Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Recurium Ip Holdings

US Patent
LigandPNGBDBM421836(US10493060, Example BVD-523)
Affinity DataIC50: 50nMAssay Description:Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
US Patent