BDBM422056 5-((7-chloro-6-fluoro-1H-indol-3- yl)methyl)-3-(2,3- difluorobenzyl)imidazolidine-2,4- dione::US10508102, Example II-6

SMILES Fc1cccc(CN2C(=O)NC(Cc3c[nH]c4c(Cl)c(F)ccc34)C2=O)c1F

InChI Key InChIKey=WTEBWRVJWJLYHT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 422056   

TargetTumor necrosis factor(Human)
President and Fellows of Harvard College

US Patent
LigandPNGBDBM422056(US10508102, Example II-6 | 5-((7-chloro-6-fluoro-1...)
Affinity DataEC50:  50nMAssay Description:Compound (Ia) was prepared according to the general methods described above. Compound (Ia) and compound A (below) were screened for anti-necrotic act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetTumor necrosis factor(Human)
President and Fellows of Harvard College

US Patent
LigandPNGBDBM422056(US10508102, Example II-6 | 5-((7-chloro-6-fluoro-1...)
Affinity DataEC50:  822nMAssay Description:Compound (Ia) was prepared according to the general methods described above. Compound (Ia) and compound A (below) were screened for anti-necrotic act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent