BDBM422295 2-butyl-1- [cyclopropyl)phenyl) methyl]-6-hydroxy-5-[4- (3-methylpyridin-4- yl)benzenesulfonyl]- 1,4-dihydropyrimidin-4- one::US10508104, Example 201

SMILES CCCCc1nc(=O)c(c(O)n1C(C1CC1)c1ccccc1)S(=O)(=O)c1ccc(cc1)-c1ccncc1C

InChI Key InChIKey=QKMOVQIGEQRULU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 422295   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM422295(2-butyl-1- [cyclopropyl)phenyl) methyl]-6-hydroxy-...)
Affinity DataEC50:  5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent