BDBM422312 5-(4- bromobenzenesulfonyl)- 2-butyl-3-[(1S)-1-(3- fluorophenyl)propyl]-6- hydroxy-3,4- dihydropyrimidin-4-one::US10508104, Example 216

SMILES CCCCc1nc(O)c(c(=O)n1[C@@H](CC)c1cccc(F)c1)S(=O)(=O)c1ccc(Br)cc1

InChI Key InChIKey=KOBGJVUTTLVZBP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 422312   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM422312(5-(4- bromobenzenesulfonyl)- 2-butyl-3-[(1S)-1-(3-...)
Affinity DataEC50:  5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent