BDBM422315 3-[(1S)-1-(2H-1,3- benzodioxol-5- yl)propyl]-5-(4- bromobenzenesulfonyl)- 2-butyl-6-hydroxy-3,4- dihydropyrimidin-4-one::US10508104, Example 219

SMILES CCCCc1nc(O)c(c(=O)n1[C@@H](CC)c1ccc2OCOc2c1)S(=O)(=O)c1ccc(Br)cc1

InChI Key InChIKey=HXUGVIVFIQQHGC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 422315   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM422315(3-[(1S)-1-(2H-1,3- benzodioxol-5- yl)propyl]-5-(4-...)
Affinity DataEC50:  5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent