BDBM422731 US10508105, Compound 125::US10508105, Compound 136::US10508105, Compound 80

SMILES Cn1nc(OC[C@H]2CCOC2)c2ccc(NC(=O)c3ncccc3N)cc12

InChI Key InChIKey=BRJSTKRLZTZDHN-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 422731   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM422731(US10508105, Compound 125 | US10508105, Compound 13...)
Affinity DataEC50:  24.2nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiatior of metabotropic glutamate receptor activity, in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM422731(US10508105, Compound 125 | US10508105, Compound 13...)
Affinity DataEC50:  36.9nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiatior of metabotropic glutamate receptor activity, in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM422731(US10508105, Compound 125 | US10508105, Compound 13...)
Affinity DataEC50:  36.9nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiatior of metabotropic glutamate receptor activity, in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent