BDBM42279 4-(4-Ethyl-piperazin-1-yl)-2-pyridin-3-yl-quinazoline::4-(4-ethyl-1-piperazinyl)-2-(3-pyridinyl)quinazoline;hydrochloride::4-(4-ethylpiperazin-1-yl)-2-pyridin-3-yl-quinazoline;hydrochloride::4-(4-ethylpiperazin-1-yl)-2-pyridin-3-ylquinazoline;hydrochloride::4-(4-ethylpiperazino)-2-(3-pyridyl)quinazoline;hydrochloride::MLS000069125::SMR000011754::cid_6603177

SMILES FCCOC[C@H]1CN(CCN1C1=NC=NC=N1)C1=NC=C(C=N1)/C=C/C=1C=CC(=NC1)C1=CN=CO1

InChI Key InChIKey=JGJMAGYJXPIPPW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42279   

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42279BDBM42279((R,E)-5-(5-(2-(2-(3-((2-fluoroethoxy)methyl)-4-(1,...)
Affinity DataKi:  0.800nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAmyloid-beta precursor protein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42279BDBM42279((R,E)-5-(5-(2-(2-(3-((2-fluoroethoxy)methyl)-4-(1,...)
Affinity DataKi:  1.20E+3nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent