BDBM42295 MLS000034000::SMR000013789::[4-(3,5-Dimethyl-phenyl)-piperazin-1-yl]-morpholin-4-yl-methanone::[4-(3,5-dimethylphenyl)-1-piperazinyl]-(4-morpholinyl)methanone::[4-(3,5-dimethylphenyl)piperazin-1-yl]-morpholin-4-yl-methanone::[4-(3,5-dimethylphenyl)piperazin-1-yl]-morpholin-4-ylmethanone::[4-(3,5-dimethylphenyl)piperazino]-morpholino-methanone::cid_656229

SMILES FCN1N=CC(=C1)C1=NC=C(C=N1)C#CC=1C=NC(=NC1)N1C[C@@H](N(CC1)C1=NC=NC=N1)COC

InChI Key InChIKey=LNMNXZAVKYHJKL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 42295   

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42295BDBM42295((R)-2-(4-(5-((2-(1-(fluoromethyl)-1H-pyrazol-4-yl)...)
Affinity DataKi:  0.640nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent