BDBM42300 MLS000042121::N-(1,1-diketothiolan-3-yl)-2-(2-methylphenoxy)-N-(2-thenyl)acetamide::N-(1,1-dioxo-3-thiolanyl)-2-(2-methylphenoxy)-N-(thiophen-2-ylmethyl)acetamide::N-(1,1-dioxothiolan-3-yl)-2-(2-methylphenoxy)-N-(thiophen-2-ylmethyl)acetamide::N-[1,1-bis(oxidanylidene)thiolan-3-yl]-2-(2-methylphenoxy)-N-(thiophen-2-ylmethyl)ethanamide::SMR000043236::cid_662623

SMILES N1(C=NC=C1)C1=CC=C(C=N1)C#CC=1C=NC(=NC1)N1C[C@@H](N(CC1)C1=NC(=NC=C1)F)COC

InChI Key InChIKey=QBMMXPBKICXZMV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42300   

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42300BDBM42300((R)-4-(4-(5-((6-(1H-imidazol-1-yl)pyridin-3-yl)eth...)
Affinity DataKi:  1.49nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAmyloid-beta precursor protein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42300BDBM42300((R)-4-(4-(5-((6-(1H-imidazol-1-yl)pyridin-3-yl)eth...)
Affinity DataKi:  1.20E+3nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent