BDBM423293 US10501451, Example 15, P-1::US10501451, Example 15, P-2

SMILES Oc1ccc(cc1)[C@@H]1CCN(C[C@H]1F)C1CCON(Cc2ccc(F)cc2)C1=O

InChI Key InChIKey=NXDMPSWVSBJLBA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 423293   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423293(US10501451, Example 15, P-2 | US10501451, Example ...)
Affinity DataKi:  12.5nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423293(US10501451, Example 15, P-2 | US10501451, Example ...)
Affinity DataKi:  393nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent