BDBM423308 US10501452, Compound 14

SMILES CN1CCc2ccc(OCCCN3CCN(CC3)c3nsc4ccccc34)cc2C1=O

InChI Key InChIKey=OFGVTQBDSWPSFF-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 423308   

TargetD(2) dopamine receptor(Human)
Nhwa Pharma.

US Patent
LigandPNGBDBM423308(US10501452, Compound 14)
Affinity DataKi:  6.90nMAssay Description:D2:Procedures(1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Nhwa Pharma.

US Patent
LigandPNGBDBM423308(US10501452, Compound 14)
Affinity DataKi:  7.20nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Rat)
Nhwa Pharma.

US Patent
LigandPNGBDBM423308(US10501452, Compound 14)
Affinity DataKi:  8.80nMAssay Description:5-HT1A: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 7(Rat)
Nhwa Pharma.

US Patent
LigandPNGBDBM423308(US10501452, Compound 14)
Affinity DataKi:  16.8nMAssay Description:5-HT7: (1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetHistamine H1 receptor(Rat)
Nhwa Pharma.

US Patent
LigandPNGBDBM423308(US10501452, Compound 14)
Affinity DataKi:  1.36E+3nMAssay Description:Histamine H1: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent