BDBM423331 US10501458, Compound 1004

SMILES CC(=O)N1CCC(CC1)c1cc(cn2cncc12)C(F)(F)F

InChI Key InChIKey=FUPFKFXLYRBUEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 423331   

TargetTryptophan 2,3-dioxygenase(Human)
Iomet Pharma

US Patent
LigandPNGBDBM423331(US10501458, Compound 1004)
Affinity DataIC50: 300nMAssay Description:Recombinant human IDO or TDO was incubated in 50 mM KPO4 (pH 7.0), 0.5 mM EGTA, 0.5 mM EDTA, 0.05% Triton X100, 20 mM ascorbate, 10 μM methylene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iomet Pharma

US Patent
LigandPNGBDBM423331(US10501458, Compound 1004)
Affinity DataIC50: 6.62E+4nMAssay Description:Recombinant human IDO or TDO was incubated in 50 mM KPO4 (pH 7.0), 0.5 mM EGTA, 0.5 mM EDTA, 0.05% Triton X100, 20 mM ascorbate, 10 μM methylene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent