BDBM423362 3-methyl-5-{1-[7- (trifluoromethyl)imidazo[1, 5-a]pyridin-5-yl]piperidin- 4-yl}isoxazole-4- carboxamide::US10501458, Compound 1035

SMILES Cc1noc(C2CCN(CC2)c2cc(cc3cncn23)C(F)(F)F)c1C(N)=O

InChI Key InChIKey=HXZNHYCUQHGYGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423362   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iomet Pharma

US Patent
LigandPNGBDBM423362(3-methyl-5-{1-[7- (trifluoromethyl)imidazo[1, 5-a]...)
Affinity DataIC50: 251nMAssay Description:Compounds to be tested were serially diluted in ten 3-fold steps in DMSO starting from 10 mM DMSO stocks. Compound dilutions or DMSO alone were then ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent