BDBM423363 N,3-dimethyl-5-{1-[7- (trifluoromethyl)imidazo[1, 5-a]pyridin-5-yl]piperidin- 4-yl}isoxazole-4- carboxamide::US10501458, Compound 1036

SMILES CNC(=O)c1c(C)noc1C1CCN(CC1)c1cc(cc2cncn12)C(F)(F)F

InChI Key InChIKey=CNJWHHUVWWGGQE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423363   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iomet Pharma

US Patent
LigandPNGBDBM423363(N,3-dimethyl-5-{1-[7- (trifluoromethyl)imidazo[1, ...)
Affinity DataIC50: 398nMAssay Description:Compounds to be tested were serially diluted in ten 3-fold steps in DMSO starting from 10 mM DMSO stocks. Compound dilutions or DMSO alone were then ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent