BDBM423364 6-amino-1,3-dimethyl-5-{4- [7- (trifluoromethyl)imidazo[1, 5-a]pyridin-5-yl]piperazin- 1-yl}pyrimidine- 2,4(1H,3H)-dione::US10501458, Compound 1037

SMILES Cn1c(N)c(N2CCN(CC2)c2cc(cc3cncn23)C(F)(F)F)c(=O)n(C)c1=O

InChI Key InChIKey=MMOWNZZQUXLSMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423364   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iomet Pharma

US Patent
LigandPNGBDBM423364(6-amino-1,3-dimethyl-5-{4- [7- (trifluoromethyl)im...)
Affinity DataIC50: 794nMAssay Description:Compounds to be tested were serially diluted in ten 3-fold steps in DMSO starting from 10 mM DMSO stocks. Compound dilutions or DMSO alone were then ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent