BDBM423410 WO2005113580-Ex-03::cmdc.202100576, 6d

SMILES COCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)c1cc2c(OC)cccc2[nH]1

InChI Key InChIKey=DDBOBUWAMRFUJW-SNRMKQJTSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 423410   

TargetReplicase polyprotein 1ab(SARS-CoV)
Pfizer

WIPO
LigandPNGBDBM423410(WO2005113580-Ex-03 | cmdc.202100576, 6d)
Affinity DataIC50:  51nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2005113580


TargetReplicase polyprotein 1ab(SARS-CoV)
Pfizer

WIPO
LigandPNGBDBM423410(WO2005113580-Ex-03 | cmdc.202100576, 6d)
Affinity DataIC50:  51nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetReplicase polyprotein 1ab(SARS-CoV)
Pfizer

WIPO
LigandPNGBDBM423410(WO2005113580-Ex-03 | cmdc.202100576, 6d)
Affinity DataEC50:  3.10E+4nMAssay Description:Protection from SARS Infection: Neutral Red Endpoint The ability of compounds to protect cells against infection by the SARS coronavirus is measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2005113580