BDBM425051 N-[(2S)-1-[1,4-Diazabicyclo[3.2.2]nonan-4- yl]-5-[[(1R,2S)-2-(4- fluorophenyl)cyclopropyl]amino]-1- oxopentan-2-yl]-4-(1H-1,2,3-triazol-1- yl)benzamide::US10519118, Example 123::US11230534, Example 123

SMILES O=C(N[C@@H](CCCN[C@@H]1C[C@H]1c1ccc(F)cc1)C(=O)N1CCN2CCC1CC2)c1ccc(-n2ccnn2)cc1

InChI Key InChIKey=WGTDDZDFFWSDNE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 425051   

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 425051BDBM425051(US10519118, Example 123 | N-[(2S)-1-[1,4-Diazabicy...)
Affinity DataIC50: 6.00E+3nMAssay Description:Briefly, bulk histones, histone peptides or nucleosomes are incubated with purified human recombinant KDM1A, in the histone demethylase activity (HDM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 425051BDBM425051(US10519118, Example 123 | N-[(2S)-1-[1,4-Diazabicy...)
Affinity DataIC50: 6.00E+3nMAssay Description:The KDM1A demethylase enzyme activity can obtained from mammalian cells or tissues expressing KDM1A from an endogenous or recombinant gene and purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2022
Entry Details
US Patent