BDBM425052 N-[(2S)-5-[[(1R,2S)-2-(4- Fluorophenyl)cyclopropyl]amino]-1-(1,4- diazabicyclo[3.2.2]nonane-1-yl)-1- oxopentan-2-yl]-4-(pyrimidin-2- yl)benzamide::US10519118, Example 124::US11230534, Example 124

SMILES O=C(N[C@@H](CCCN[C@@H]1C[C@H]1c1ccc(F)cc1)C(=O)N1CCN2CCC1CC2)c1ccc(-c2ncccn2)cc1

InChI Key InChIKey=GZQKCYLZLPTGBA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 425052   

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 425052BDBM425052(US10519118, Example 124 | N-[(2S)-5-[[(1R,2S)-2-(4...)
Affinity DataIC50: 8.00E+3nMAssay Description:Briefly, bulk histones, histone peptides or nucleosomes are incubated with purified human recombinant KDM1A, in the histone demethylase activity (HDM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 425052BDBM425052(US10519118, Example 124 | N-[(2S)-5-[[(1R,2S)-2-(4...)
Affinity DataIC50: 8.00E+3nMAssay Description:The KDM1A demethylase enzyme activity can obtained from mammalian cells or tissues expressing KDM1A from an endogenous or recombinant gene and purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2022
Entry Details
US Patent