BDBM425071 4-(2,5-dimethyl-1H-pyrrol-1-yl)-N-((S)-4- ((1R,2S)-2-(4- fluorophenyl)cyclopropylamino)-1-oxo-1- (thiomorpholino-4,4-dioxide-1-yl)-butan-2- yl)benzamide::US10519118, Example 148::US11230534, Example 148

SMILES Cc1ccc(C)n1-c1ccc(cc1)C(=O)N[C@@H](CCN[C@@H]1C[C@H]1c1ccc(F)cc1)C(=O)N1CCS(=O)(=O)CC1

InChI Key InChIKey=MIRGDJGVUMHDQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 425071   

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM425071(US10519118, Example 148 | 4-(2,5-dimethyl-1H-pyrro...)
Affinity DataIC50: 5.00E+3nMAssay Description:Briefly, bulk histones, histone peptides or nucleosomes are incubated with purified human recombinant KDM1A, in the histone demethylase activity (HDM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM425071(US10519118, Example 148 | 4-(2,5-dimethyl-1H-pyrro...)
Affinity DataIC50: 5.00E+3nMAssay Description:The KDM1A demethylase enzyme activity can obtained from mammalian cells or tissues expressing KDM1A from an endogenous or recombinant gene and purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2022
Entry Details
US Patent