BDBM425102 N-((S)-5-((1R,2S)-2-(4- fluorophenyl)cyclopropylamino)-1- morpholino-1-oxopentan-2-yl)-4-(1H- pyrazol-1-yl)benzamide::US10519118, Example 177::US11230534, Example 177

SMILES Fc1ccc(cc1)[C@@H]1C[C@H]1NCCC[C@H](NC(=O)c1ccc(cc1)-n1cccn1)C(=O)N1CCOCC1

InChI Key InChIKey=MRLIKNBYGUGUCT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 425102   

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM425102(US10519118, Example 177 | N-((S)-5-((1R,2S)-2-(4- ...)
Affinity DataIC50: 2.00E+3nMAssay Description:Briefly, bulk histones, histone peptides or nucleosomes are incubated with purified human recombinant KDM1A, in the histone demethylase activity (HDM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM425102(US10519118, Example 177 | N-((S)-5-((1R,2S)-2-(4- ...)
Affinity DataIC50: 2.00E+3nMAssay Description:The KDM1A demethylase enzyme activity can obtained from mammalian cells or tissues expressing KDM1A from an endogenous or recombinant gene and purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2022
Entry Details
US Patent