BDBM425111 4'-fluoro-N-((S)-4-((1R,2S)-2-(4- fluorophenyl)cyclopropylamino)-1-oxo-1- (thiomorpholino-4,4-dioxide-1-yl)-butan-2- yl)biphenyl-4-carboxamide::US10519118, Example 187

SMILES CS(=O)(=O)N1CCN(CC1)C(=O)[C@H](CCCCN[C@H]1C[C@@H]1c1ccc(F)cc1)NC(=O)c1ccc(cc1)-c1ccc(F)cc1

InChI Key InChIKey=CBTSIHOWWLSSAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425111   

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM425111(US10519118, Example 187 | 4'-fluoro-N-((S)-4-((1R,...)
Affinity DataIC50: 4.00E+3nMAssay Description:Briefly, bulk histones, histone peptides or nucleosomes are incubated with purified human recombinant KDM1A, in the histone demethylase activity (HDM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent