BDBM425201 US10519163, Example 98

SMILES NCC1(CC(O)c2ccccc12)c1cccc(c1)-c1ncnc2[nH]ccc12

InChI Key InChIKey=UAPASVZOUSSSPZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 425201   

TargetTyrosine-protein kinase receptor UFO(Human)
Incyte

US Patent
LigandPNGBDBM425201(US10519163, Example 98)
Affinity DataIC50: 500nMAssay Description:The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Incyte

US Patent
LigandPNGBDBM425201(US10519163, Example 98)
Affinity DataIC50: 500nMAssay Description:The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
Incyte

US Patent
LigandPNGBDBM425201(US10519163, Example 98)
Affinity DataIC50: 750nMAssay Description:The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
Incyte

US Patent
LigandPNGBDBM425201(US10519163, Example 98)
Affinity DataIC50: 750nMAssay Description:The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Incyte

US Patent
LigandPNGBDBM425201(US10519163, Example 98)
Affinity DataIC50: 750nMAssay Description:The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Incyte

US Patent
LigandPNGBDBM425201(US10519163, Example 98)
Affinity DataIC50: 2.00E+3nMAssay Description:The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent