BDBM42541 1-Benzyl-4-phenyl-decahydro-quinolin-4-ol::1-benzyl-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-4-ol;hydrochloride::4-phenyl-1-(phenylmethyl)-2,3,4a,5,6,7,8,8a-octahydroquinolin-4-ol;hydrochloride::MLS000562811::SMR000177702::cid_12004707

SMILES C=CC(=O)N1CCc2nn(-c3ccc(C4CCC4)cc3O)c3c2C(C1)N(C(=O)c1ccc(SC(F)(F)F)nc1)CC3

InChI Key InChIKey=BIWOHGQOCMGKSL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42541   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [2-1432](Human)
MOMA Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 42541BDBM42541(1-(2-(4-cyclobutyl-2- hydroxyphenyl)-5-(6- ((trifl...)
Affinity DataIC50: 1.5nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute (TSRI) Assay Provid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details US Patent

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [2-1432](Human)
MOMA Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 42541BDBM42541(1-(2-(4-cyclobutyl-2- hydroxyphenyl)-5-(6- ((trifl...)
Affinity DataIC50: 10nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute (TSRI) Assay Provid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details US Patent