BDBM42544 3-(4-butoxyphenyl)-4,5-dihydro-1H-pyridazin-6-one::6-(4-butoxyphenyl)-4,5-dihydropyridazin-3(2H)-one::MLS000584700::SMR000203663::cid_12004848

SMILES C=CC(=O)N1CC(O)c2nn(-c3ccc(C4CCC4)cc3)c3c2C(C1)N(C(=O)c1ccc(Br)c2c1=NC(C(F)F)N=2)CC3

InChI Key InChIKey=UCBSDEIESXJXND-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42544   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [2-1432](Human)
MOMA Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 42544BDBM42544(1-(5-(7-bromo-2- (difluoromethyl)-1H- benzo[d]imid...)
Affinity DataIC50: 1.5nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute (TSRI) Assay Provid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details US Patent

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [2-1432](Human)
MOMA Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 42544BDBM42544(1-(5-(7-bromo-2- (difluoromethyl)-1H- benzo[d]imid...)
Affinity DataIC50: 3.25nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute (TSRI) Assay Provid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details US Patent