BDBM42548 (Z)-2-Benzoylamino-3-(9-methyl-9H-carbazol-3-yl)-acrylic acid isopropyl ester::(Z)-2-benzamido-3-(9-methyl-3-carbazolyl)-2-propenoic acid propan-2-yl ester::(Z)-2-benzamido-3-(9-methylcarbazol-3-yl)acrylic acid isopropyl ester::MLS000590005::SMR000217189::cid_1915932::propan-2-yl (Z)-2-benzamido-3-(9-methylcarbazol-3-yl)prop-2-enoate

SMILES C=CC(=O)N1CCc2nn(-c3ccc(C4CC4)cc3O)c3c2C(C1)N(C(=O)c1cnc(C(F)(F)F)cc1N)CC3

InChI Key InChIKey=SDLQWKGKPVLOJF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42548   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [2-1432](Human)
MOMA Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 42548BDBM42548(1-(5-(4-amino-6- (trifluoromethyl) nicotinoyl)- 2-...)
Affinity DataIC50: 1.5nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute (TSRI) Assay Provid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details US Patent

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [2-1432](Human)
MOMA Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 42548BDBM42548(1-(5-(4-amino-6- (trifluoromethyl) nicotinoyl)- 2-...)
Affinity DataIC50: 10nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute (TSRI) Assay Provid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details US Patent