BDBM425873 2-(4-tert-butylphenyl)-N- hydroxy-1H-benzimidazole- 6-carboxamide::US10512634, Example 159

SMILES CC(C)(C)c1ccc(cc1)-c1nc2ccc(cc2[nH]1)C(=O)NO

InChI Key InChIKey=MKVPVGHBSKZVON-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425873   

TargetHistone deacetylase 6(Human)
Kancera

US Patent
LigandPNGBDBM425873(2-(4-tert-butylphenyl)-N- hydroxy-1H-benzimidazole...)
Affinity DataIC50: 19nMAssay Description:All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
US Patent