BDBM425933 US10512644, Compound 6-O-mPEG3-Nalbuphine

SMILES COCCOCCOCCO[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CCC1)c45

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 425933   

TargetMu-type opioid receptor(Human)
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425933(US10512644, Compound 6-O-mPEG3-Nalbuphine)
Affinity DataKi:  27.4nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425933(US10512644, Compound 6-O-mPEG3-Nalbuphine)
Affinity DataKi:  163nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425933(US10512644, Compound 6-O-mPEG3-Nalbuphine)
Affinity DataKi:  218nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
US Patent