BDBM426542 4-[3-[[(1S,5R)-3- azabicyclo[3.1.0]hexan-6- yl]methylamino]-5-(4- methylphenyl)pyrazol-1- yl]benzonitrile::US10543198, Example 47::US10864202, Example 47

SMILES Cc1ccc(cc1)-c1cc(NC[C@H]2[C@@H]3CNC[C@H]23)nn1-c1ccc(cc1)C#N

InChI Key InChIKey=HOMPZWLAASQFNG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426542   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM426542(US10543198, Example 47 | 4-[3-[[(1S,5R)-3- azabicy...)
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM426542(US10543198, Example 47 | 4-[3-[[(1S,5R)-3- azabicy...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent