BDBM426559 2-fluoro-4-[6-[4- (methylamino)piperidin-1-yl]-3-(1- propan-2-ylbenzimidazol-5- yl)pyrazin-2-yl]benzonitrile::US10543198, Example 63::US10864202, Example 63

SMILES CNC1CCN(CC1)c1cnc(-c2ccc(OC)c(F)c2)c(n1)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=OCYSAWWHUGWZCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426559   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM426559(US10543198, Example 63 | 2-fluoro-4-[6-[4- (methyl...)
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM426559(US10543198, Example 63 | 2-fluoro-4-[6-[4- (methyl...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent