BDBM426571 4-[6-(4-aminopiperidin-1-yl)-3- (6,7-difluoro-1-propan-2- ylbenzimidazol-5-yl)pyrazin-2-yl]- 2-fluorobenzonitrile::US10543198, Example 73::US10864202, Example 73

SMILES CC(C)n1cnc2cc(c(F)c(F)c12)-c1ncc(nc1-c1ccc(C#N)c(F)c1)N1CCC(N)CC1

InChI Key InChIKey=GBULVMZWXLGNTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426571   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM426571(US10543198, Example 73 | 4-[6-(4-aminopiperidin-1-...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM426571(US10543198, Example 73 | 4-[6-(4-aminopiperidin-1-...)
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent