BDBM426647 US10544095, Example 32

SMILES Fc1ccc2c(c[nH]c2c1)-c1ccc(c(c1)C#N)S(=O)(=O)N1CCNCC1

InChI Key InChIKey=FWBDVIKJBWDAFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426647   

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426647(US10544095, Example 32)
Affinity DataIC50: 730nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent