BDBM427080 US10544132, Example 35

SMILES CC(C)(O)c1cc2C(=O)N(Cc3ccc(Cl)cc3S(C)(=O)=O)C(OCC3(CC3)C(N)=O)(c2c(F)c1)c1ccc(Cl)cc1

InChI Key InChIKey=QXTIAAQSOXPAAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 427080   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandPNGBDBM427080(US10544132, Example 35)
Affinity DataIC50:  1.80nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent