BDBM427121 US10544132, Example 68

SMILES CN1CCN(C[C@@](C)(O)c2cc3C(=O)N(Cc4ccc(Cl)cc4S(C)(=O)=O)[C@](O[C@@H]4CCOC4)(c3c(F)c2)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=GEZPZMXREXHEJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 427121   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandPNGBDBM427121(US10544132, Example 68)
Affinity DataIC50: 7nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent