BDBM427252 US10544136, Compound 61

SMILES Nc1cc(ccn1)-c1noc(n1)-c1ccc(-c2ccccc2)c(c1)C(F)(F)F

InChI Key InChIKey=MNUOZSIAEZBHST-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 427252   

TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM427252(US10544136, Compound 61)
Affinity DataEC50:  0.780nMAssay Description:The method involves contacting the receptor with a suitable concentration of an inventive compound to bring about activation of the receptor. The con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 3(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM427252(US10544136, Compound 61)
Affinity DataEC50:  1.32E+3nMAssay Description:The method involves contacting the receptor with a suitable concentration of an inventive compound to bring about activation of the receptor. The con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent