BDBM427431 US10544136, Compound 215::US10544136, Compound 216

SMILES CCOc1ccc(cc1OCC)-c1nc(no1)-c1cccc2C(CCc12)NC(C)(C)CO

InChI Key InChIKey=UXQOTHZPRBCDJX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 427431   

TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM427431(US10544136, Compound 215 | US10544136, Compound 21...)
Affinity DataEC50:  0.100nMAssay Description:The method involves contacting the receptor with a suitable concentration of an inventive compound to bring about activation of the receptor. The con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM427431(US10544136, Compound 215 | US10544136, Compound 21...)
Affinity DataEC50:  91.5nMAssay Description:The method involves contacting the receptor with a suitable concentration of an inventive compound to bring about activation of the receptor. The con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent