BDBM427462 US10544136, Compound 248::US10544136, Compound 250

SMILES CCOc1ccc(cc1OCC)-c1nc(no1)-c1cccc2C(CCc12)N1CC[C@@H](O)C1

InChI Key InChIKey=GEHYWVCUTZBENZ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 427462   

TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM427462(US10544136, Compound 248 | US10544136, Compound 25...)
Affinity DataEC50:  1.5nMAssay Description:The method involves contacting the receptor with a suitable concentration of an inventive compound to bring about activation of the receptor. The con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM427462(US10544136, Compound 248 | US10544136, Compound 25...)
Affinity DataEC50:  6.10nMAssay Description:The method involves contacting the receptor with a suitable concentration of an inventive compound to bring about activation of the receptor. The con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 3(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM427462(US10544136, Compound 248 | US10544136, Compound 25...)
Affinity DataEC50:  2.30E+3nMAssay Description:The method involves contacting the receptor with a suitable concentration of an inventive compound to bring about activation of the receptor. The con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent