BDBM428663 (R or S)-3-benzyl-5-(9-ethyl- 8-(2-methylpyrimidin-5-yl)- 9H-purin-6-yl)-1,3- dimethylindolin-2-one::US10544147, Compound 1-20::US10544147, Compound 1-21

SMILES CCn1c(nc2c(ncnc12)-c1ccc2N(C)C(=O)C(C)(Cc3ccccc3)c2c1)-c1cnc(C)nc1

InChI Key InChIKey=IUIWKCKTCDYVGW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 428663   

LigandPNGBDBM428663(US10544147, Compound 1-20 | US10544147, Compound 1...)
Affinity DataIC50: 4nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

LigandPNGBDBM428663(US10544147, Compound 1-20 | US10544147, Compound 1...)
Affinity DataIC50: 477nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent