BDBM428668 (R or S)-3- (cyclopropylmethyl)-5-(9- ethyl-8-(1-ethyl-5-methyl- 1H-pyrazol-4-yl)-9H-purin-6- yl)-3-methylindolin-2-one::US10544147, Compound 1-25

SMILES CCn1ncc(c1C)-c1nc2c(ncnc2n1CC)-c1ccc2NC(=O)C(C)(CC3CC3)c2c1

InChI Key InChIKey=NGPYJBHDUFFSRB-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 428668   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM428668((R or S)-3- (cyclopropylmethyl)-5-(9- ethyl-8-(1-e...)Copy SMILESCopy InChI

Affinity DataIC50: 4nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/2/2020
Entry Details
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