BDBM428669 (R or S)-3-isobutyl-3-methyl- 5-(9-methyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6-yl)-1,3-dihydro-2H- pyrrolo[2,3-b]pyridin-2-one::US10544147, Compound 1-26::US10544147, Compound 1-27

SMILES CC(C)CC1(C)C(=O)Nc2ncc(cc12)-c1ncnc2n(C)c(nc12)-c1cnc(C)nc1

InChI Key InChIKey=KBLJFWBEGWWJDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 428669   

LigandPNGBDBM428669((R or S)-3-isobutyl-3-methyl- 5-(9-methyl-8-(2- me...)
Affinity DataIC50: 5nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

LigandPNGBDBM428669((R or S)-3-isobutyl-3-methyl- 5-(9-methyl-8-(2- me...)
Affinity DataIC50: 50nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent