BDBM428673 US10544147, Compound 1-30::US10544147, Compound 1-31::US10544147, Compound 1-32::[(R,R) or (R,S) or (S,S) or (S,R)]-5-(9-ethyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6-yl)-3-methyl-3- (oxetan-2-ylmethyl)indolin- 2-one

SMILES CCn1c(nc2c(ncnc12)-c1ccc2NC(=O)C(C)(CC3CCO3)c2c1)-c1cnc(C)nc1

InChI Key InChIKey=IFBOIWZLZHJWHB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 428673   

LigandPNGBDBM428673([(R,R) or (R,S) or (S,S) or (S,R)]-5-(9-ethyl-8-(2...)
Affinity DataIC50: 3nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

LigandPNGBDBM428673([(R,R) or (R,S) or (S,S) or (S,R)]-5-(9-ethyl-8-(2...)
Affinity DataIC50: 7nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

LigandPNGBDBM428673([(R,R) or (R,S) or (S,S) or (S,R)]-5-(9-ethyl-8-(2...)
Affinity DataIC50: 159nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent