BDBM428689 (R or S)-1-{5-[9-ethyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6-yl]-3-methyl-2- oxo-2,3-dihydro-1H-indol- 3-yl}-3-methylazetidine-3- carbonitrile::US10544147, Compound 2-5::US10544147, Compound 2-6

SMILES CCn1c(nc2c(ncnc12)-c1ccc2NC(=O)C(C)(N3CC(C)(C3)C#N)c2c1)-c1cnc(C)nc1

InChI Key InChIKey=UOCQTOBGRHWEQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 428689   

LigandPNGBDBM428689(US10544147, Compound 2-6 | (R or S)-1-{5-[9-ethyl-...)
Affinity DataIC50: 3nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

LigandPNGBDBM428689(US10544147, Compound 2-6 | (R or S)-1-{5-[9-ethyl-...)
Affinity DataIC50: 73nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent