BDBM428719 5-[9-ethyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6-yl]-3(R or S)- methyl-3-[(3S)- tetrahydrofuran-3- ylamino]-1,3-dihydro-2H- indol-2-one::US10544147, Compound 2-35::US10544147, Compound 2-36

SMILES CCn1c(nc2c(ncnc12)-c1ccc2NC(=O)C(C)(N[C@H]3CCOC3)c2c1)-c1cnc(C)nc1

InChI Key InChIKey=OXTNSSBZJXRCGW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 428719   

LigandPNGBDBM428719(US10544147, Compound 2-36 | 5-[9-ethyl-8-(2- methy...)
Affinity DataIC50: 4nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

LigandPNGBDBM428719(US10544147, Compound 2-36 | 5-[9-ethyl-8-(2- methy...)
Affinity DataIC50: 1.33E+3nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent