BDBM428729 (R or S)-3-methyl-5-(9- methyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6-yl)-3-(((S)- tetrahydrofuran-3- yl)amino)-1H-pyrrolo[2,3- b]pyridin-2(3H)-one::US10544147, Compound 2-45::US10544147, Compound 2-46

SMILES Cc1ncc(cn1)-c1nc2c(ncnc2n1C)-c1cnc2NC(=O)C(C)(N[C@H]3CCOC3)c2c1

InChI Key InChIKey=KOJUGTUREQCBQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 428729   

LigandPNGBDBM428729(US10544147, Compound 2-45 | US10544147, Compound 2...)
Affinity DataIC50: 7nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

LigandPNGBDBM428729(US10544147, Compound 2-45 | US10544147, Compound 2...)
Affinity DataIC50: 748nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent