BDBM428731 (R or S)-5-(9-ethyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6-yl)-3-(3-methoxy- 3-methylazetidin-1-yl)-3- methyl-1H-pyrrolo[2,3- b]pyridin-2(3H)-one::US10544147, Compound 2-47::US10544147, Compound 2-48

SMILES CCn1c(nc2c(ncnc12)-c1cnc2NC(=O)C(C)(N3CC(C)(C3)OC)c2c1)-c1cnc(C)nc1

InChI Key InChIKey=PDSQZLIADJZUSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 428731   

LigandPNGBDBM428731(US10544147, Compound 2-47 | (R or S)-5-(9-ethyl-8-...)
Affinity DataIC50: 4nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

LigandPNGBDBM428731(US10544147, Compound 2-47 | (R or S)-5-(9-ethyl-8-...)
Affinity DataIC50: 509nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent