BDBM428768 (R or S)-1''- (cyclopropylcarbonyl)-5-[9- ethyl-8-(2-methylpyrimidin-5- yl)-9H-purin-6- yl]spiro[indole-3,2''- pyrrolidin]-2(1H)-one::US10544147, Compound 3-1::US10544147, Compound 3-2

SMILES CCn1c(nc2c(ncnc12)-c1ccc2NC(=O)C3(CCCN3C(=O)C3CC3)c2c1)-c1cnc(C)nc1

InChI Key InChIKey=BIMJIXDSAJMYAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 428768   

LigandPNGBDBM428768(US10544147, Compound 3-2 | (R or S)-1''- (cyclopro...)
Affinity DataIC50: 1nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

LigandPNGBDBM428768(US10544147, Compound 3-2 | (R or S)-1''- (cyclopro...)
Affinity DataIC50: 39nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent