BDBM428774 (R or S)-1'- (cyclopropanecarbonyl)-5-(9- methyl-8-(2-methylpyrimidin- 5-yl)-9H-purin-6- yl)spiro[indoline-3,2'- pyrrolidin]-2-one::US10544147, Compound 3-7

SMILES Cc1ncc(cn1)-c1nc2c(ncnc2n1C)-c1ccc2NC(=O)C3(CCCN3C(=O)C3CC3)c2c1

InChI Key InChIKey=YTVZJQCTBUIDMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 428774   

LigandPNGBDBM428774((R or S)-1'- (cyclopropanecarbonyl)-5-(9- methyl-8...)
Affinity DataIC50: 1nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent